Regenerative Capacity of Macrophages for Remyelination

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Regenerative Capacity of Macrophages for Remyelination

White matter injury, consisting of loss of axons, myelin, and oligodendrocytes, is common in many neurological disorders and is believed to underlie several motor and sensory deficits. Remyelination is the process in which the insulative myelin sheath is restored to axons, thereby facilitating recovery from functional loss. Remyelination proceeds with oligodendrocyte precursor cells (OPCs) that...

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Epigenetic regulation of axonal regenerative capacity.

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ژورنال

عنوان ژورنال: Frontiers in Cell and Developmental Biology

سال: 2016

ISSN: 2296-634X

DOI: 10.3389/fcell.2016.00047